Despite the investment of billions of euros, there has been an inexorable decline in the discovery of new antibiotics over the last decades. In this project we aim to develop bacterial histidine-kinase (HK) inhibitors as novel broad-spectrum antibacterial (nano)medicines. Furthermore, putative mechanism of resistance to HK inhibitors and known antibiotics will be studied in order to identify targets for novel antibacterial medicines.
AND
Antibacterial (Nano)medicines Development
Welcome to AND!
News
Official start of AND
Wednesday, April 1, 2015, is the official start of AND - Antibacterial (Nano)medicines Development, an individual fellowship within the H2020 MSCA awarded to Nadya Velikova and the Host-microbe Interactomics Group at Wageningen University.
A nanodevice for delivery of antibacterial drugs to patients with cystic fibrosis
We have just submitted a letter of intent to the Cystic Fibrosis Foundation for a nanodevice for delivery of theraupetics, including antibacterials, to the lungs of patients with cystic fibrosis.
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Host organization
Funding
Partners
Institute for Molecular Recognition and Technological Development, Valencia, Spain
Macromolecular Crystallography Unit, Institute of Biomedicine, Valencia, Spain